Perimenopause isn’t just about managing the symptoms as they arise—it’s about preparing for the long-term health shifts that follow. Once menopause officially begins (marked by 12 consecutive months without a period), women face an increased risk of osteoporosis, cardiovascular disease, and mental health problems like depression due to declining oestrogen levels.
Bone health
Oestrogen plays a key role in maintaining bone density. When oestrogen levels drop, bones weaken, which increases the risk of osteoporosis and fractures. Regular bone density screenings and lifestyle changes, such as weight-bearing exercises, a calcium-rich diet and vitamin D supplements can help mitigate this risk before it becomes an issue in the future.
Heart health
Oestrogen also protects the heart, keeping arteries flexible and reducing inflammation. As levels decline, the risk of heart disease and stroke rises. That’s why postmenopausal women should be proactive about screening for cardiovascular risk factors, including cholesterol levels and blood pressure.
Mental health and cognitive function
Perimenopause and early post-menopause are associated with an increased risk of depression and other mental health concerns.
This happens because during the menopausal transition, the level of oestrogen, which has neuroprotective properties, drops. As a result, the brain undergoes structural changes that increase the risk of neurological diseases, amyloid plaque buildup (linked to Alzheimer’s disease) and loss of brain volume. These brain-related shifts can contribute to symptoms such as poor concentration, fatigue, and insomnia, which may overlap with depression and anxiety.
Oestrogen also regulates serotonin and dopamine, the brain chemicals that keep your mood balanced. When oestrogen levels change and drop, these chemicals can also decrease, leading to mood swings, increased stress, and trouble with focus and memory.
Recognising these changes early allows women to take steps to protect their mental and overall health during perimenopause and beyond.